Recently, Professor Qingzeng Zhu’s group from the Key Laboratory of Special Functional Aggregate Materials of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, has made important research progress and technical results in the field of light-responsive polysiloxane materials.
    The research group designed and synthesized a series of photo-responsive silanes, and further prepared photo-responsive polysiloxane functional materials, which achieved precise control of the release of target molecules and surface micro-patterning of protein molecules. This series of materials And technical methods have important application value in the fields of biochips and tissue engineering.
    Professor Qingzeng Zhu’s team designed and synthesized a series of light-responsive bridging silanes, and prepared a new type of light-tunable charge conversion organosilicon functional material for constructing protein micropatterns. Under light, the charge properties of the surface of the organic silicon material will change, thereby realizing the fixation and release of light-controlled proteins, and accurately forming protein micropatterns. By adjusting the irradiation parameters in time and space, the protein concentration, position, and the shape and size of the micro-patterns are precisely controlled. This light-tunable charge conversion material is used for protein micro-patterning for the first time. There are important application prospects in the medical field.

    Silicone materials are excellent carriers for biomolecules. The team has also developed a light-responsive controllable release system that can precisely control the release behavior of target molecules. Through simple and convenient light stimulation methods and gentle electrostatic interactions, the target molecules can be released. Accurate and controllable release.
    The system uses the designed and synthesized bridged polysilsesquioxane nanoparticles with light-triggered charge reversal performance as the carrier, and adjusts the light irradiation intensity, irradiation time and On/Off mode to control the release position and release time of the target molecule. , Especially the release amount, can realize multi-dimensional precise control. Such materials and technical methods can be used for the transportation and release of target molecules such as food additives, dyes, cosmetics, pesticides, ultraviolet absorbers and drugs.