December 31, 2025 - A supramolecular skincare technology jointly developed by L'Oréal China R&D and Innovation Center and Shan Hai Innovation attracted wide attention at the La Roche-Posay Supramolecular New Product Seminar. This technology has successfully solved the coordination problem between panthenol (B5) and bisabolol, two incompatible ingredients, marking a new breakthrough in skincare product development.
As a cutting-edge technology that has won the Nobel Prize in Chemistry three times, supramolecular chemistry achieves molecular self-assembly through non-covalent bonds such as hydrogen bonds and van der Waals forces. The R&D team adopted a "co-supramolecular" strategy, using diethylene glycol monoethyl ether as a bridge to construct amphiphilic transport carriers, enabling stable integration of water-soluble panthenol and oil-soluble bisabolol. Experimental verification shows that the system not only improves ingredient permeability and reduces irritation but also achieves a synergistic effect of "1+1>2".
Zhang Jiaheng, founder of Shan Hai Innovation, stated that supramolecular technology breaks the limitations of traditional materials and can be applied to more ingredient combinations such as salicylic acid and niacinamide in the future. This interdisciplinary achievement will also extend to fields such as drug delivery and biomimetic materials, injecting new vitality into the life and health industry.
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