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Do you really understand organosilicon "drug harm"?

Hits: 3896074 2020-04-28

Do you know that the so-called organosilicon can cause "drug damage"?
1. Drug damage (phytotoxicity)
The damage is basically the result of the damage of surfactants to biofilm.
Because organosilicon surfactant will enter into the medium and contact with the tissue closely, pore penetration is one aspect of drug damage. By using β - anthocyanin from beet root tissue soaked in surfactant solution, the natural cytotoxicity can be tested. The results showed that the cytotoxicity of organosilicon surfactants was lower than that of fatty amines and two ethoxyalkylphenols.
When glyphosate is added to the surfactants of fatty amines and ethoxyalcohols, there are harmful symptoms on the leaves of citronella; but when organosilicon surfactants are used, even if there are many precipitates on the leaves, there are no harmful symptoms. There was no damage to broad bean and common Chenopodium when they were treated with different organosilicon surfactants.
Organosilicon surfactants are mild to plants and are generally beneficial. The key is the harm of spray preparations. Therefore, in order to give full play to the efficacy of organosilicon surfactant, it is necessary to optimize the pesticide preparation. (focus)
2 hazards
Generally speaking, organosilicon surfactants are not more harmful than most pesticides.
Toxicological data indicate that the ingestion of organosilicon may be contrary to the expected results. It can be assumed that this is due to the rapid degradation of organosilicon in the acid environment in the stomach and then in the alkaline environment in the gut.
Because the surface tension of silicone is very low, the eyes should be protected when using silicone surfactant. In the same way, organosilicon surfactants are highly toxic to fish when entering the water, and the gill function of fish is damaged due to the decrease of surface tension. Silicone has strong penetration, high toxicity of epidermis, and may be irritating in contact with skin. Therefore, standard protective clothing should be worn during operation. Because organosilicon surfactant may penetrate into protective clothing, its toxicity is higher than that of conventional surfactant.
3 environment
There is no special report on the environmental research of organosilicon surfactants. According to the study of various pesticides, organosilicon surfactants have no difference with other additives in this respect.
In a word, organosilicon surfactant represents a kind of new and efficient pesticide additives, which has a broad application prospect, far beyond the current field. From the perspective of development, in the future, organosilicon surfactants for pesticide auxiliaries should pay attention to the exploration of the mechanism of action. Further study on the interaction between the adjuvant molecules and the effective components of pesticides and organisms (insects, plant surfaces, bacteria, etc.) will provide a reliable theoretical basis for the development and application of new and efficient organosilicon surfactants. Different pesticides and dosage forms have different requirements for organosilicon surfactants. In general, they should at least have the following characteristics: the original drug does not decompose; It can greatly reduce the surface tension of the preparation, be stable to water, acid, alkali, salt and heat, and be harmless to crops. Therefore, it is necessary to optimize the formulation of the preparation to maximize the efficacy of silicone surfactant and reduce the adverse effects.
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